- Marina Sirtis (Counsellor Deanna Troi on ST: TNG) as the morally ambiguous Demona
- Jonathan Frakes (Commander William Riker on ST: TNG) as David Xanatos, who also bears a resemblance to the actor
- Kate Mulgrew (Captain Kathryn Janeway on Voyager) as Titania
- Michael Dorn (Lieutenant Worf on both ST: TNG and ST: DS9 and Colonel Worf on Star Trek VI: The Undiscovered Country) as Coldstone and Taurus
- Brent Spiner (Commander Data, Lore, Noonien Soong, on ST: TNG, B4 on Star Trek: Nemesis, and Arik Soong on Star Trek: Enterprise) as Puck
- Nichelle Nichols (Commander Uhura on ST: TOS) as Diane Maza
- David Warner (St. John Talbot on Star Trek V: The Final Frontier and Klingon Chancellor Gorkon on Star Trek VI: The Undiscovered Country) as the Archmage
- Paul Winfield (Captain Clark Terrell on Star Trek II: The Wrath of Khan and Tamarian Captain Dathon on ST: TNG episode Darmok) as Jeffrey Robbins
- Avery Brooks (Captain Benjamin Sisko on ST: DS9) as Nokkar (guest star)
- Colm Meaney (Miles O'Brien on ST: TNG and ST: DS9) (guest star)
- LeVar Burton (Geordi La Forge on ST: TNG) as Anansi (guest star)
- John Rhys-Davies (Leonardo da Vinci on Voyager) as Macbeth
I wish they'd do a modern 3d version of the game, or another good 2D one. They just got a new comic book deal, so if it does well there may be another game in their future.
Minus 50 cool points!